Product

EpiFix

EpiFix

EpiFix is composed of human amnion and chorion membranes that comprise the innermost layer of the placenta and line the amniotic cavity. EpiFix has multiple layers including a single layer of epithelial cells, a basement membrane and an avascular connective tissue matrix.

EpiFix is intended for the treatment of acute and chronic wounds to enhance healing.

Growth Factors Present in EpiFix

Up to 285 different growth factors, specialised cytokines, and enzyme inhibitors have been identified in EpiFix. The following are some of the growth factors that help enhance healing:

  • Epidermal Growth Factor (EGF) – Promotes proliferation of epithelial cells
  • Transforming Growth Factor (TGF) – Anti-inflammatory, and promotes normal wound healing
  • Fibroblast Growth Factor (FGF) – Promotes cellular proliferation & important for collagen matrix formation
  • Platelet Derived Growth Factor A & B (PDGF A & B) – Promotes cell proliferation in connective tissue and enhances soft tissue healing

How to apply EpiFix:

  • Cut to fit
  • Apply to the wound
  • Cover to maintain a moist wound environment

Extracellular Components:

The Extracellular Matrix of amniotic membrane is composed of 3 major classes of biomolecules:

  • Structural proteins: collagen types I, III, IV, V and VII and elastin
  • Specialized proteins: fibronectin, TIMPs, and laminins
  • Proteoglycans: formed when GAGS are linked to core proteins

Product offering:

  • Multiple sizes available to reduce graft wastage
  • Available in a variety of configurations

Shelf Life: 5 years at ambient conditions

Find out more about EpiFix

EpiFix is composed of human amnion and chorion membranes that comprise the innermost layer of the placenta and line the amniotic cavity. EpiFix has multiple layers including a single layer of epithelial cells, a basement membrane and an avascular connective tissue matrix.

Contact us to find out more details about EpiFix